Monday, October 26, 2020

ASHWAGANDHA holds an efficient anti-Covid-19 property

 Ashwagandha (Withania Somnifera), commonly known as Indian winter cherry, is used in Ayurveda as a Rasayana—any preparation that improves general health by stimulating the body’s immunity. The literal meaning of Ashwagandha is “smell of horse”: The fresh roots of the herb emit the smell of a horse; also, there is a common belief that consuming extracts of the herb may help humans develop strength and vitality similar to that of a horse. The herb contains a range of constituents like withanolides and sitoindosides that protect the cells from oxidative damage and disease.

Ashwagandha has been appreciated in many cultures. There is a legend in Greek mythology in which Apollo finds this herb and gifts it to his son Asclepius—the god of medicine. There are also accounts suggesting that Alexander the Great and his army used to drink wine containing Ashwagandha to boost their energy.

The research by the IIT-D and AIST found that “natural compounds from Ashwagandha and propolis [bee glue used by bees to assemble the hive] have the potential to be effective anti-Covid-19 drug candidates”.

As part of the research, the team targeted the main protease (Mpro) of the SARS-CoV-2 virus. Mpro is a key enzyme of the Covid-19 virus, which plays a major role in mediating viral replication. They observed that Withanone, a natural compound derived from Ashwagandha have the potential to inhibit the activity of Mpro, thereby blocking replication of the virus. The study has been published in the Journal of Biomolecular Structure and Dynamics.

While publishing the findings, the researchers mentioned that the drug development for Covid-19 may take a while, and in the current scenario, easily available and affordable natural resources like Ashwagandha “may offer some preventive or even therapeutic value”.

Read more about the King of Ayurvedic Herbs - Ashwagandha

Monday, October 19, 2020

Electric shocks to the tongue can quiet Tinnitus (chronic ringing in ears)

 Tinnitus—a constant ringing or buzzing in the ears that affect about 15% of people—is difficult to understand and even harder to treat. Now, scientists have shown shocking the tongue—combined with a carefully designed sound program—can reduce symptoms of the disorder, not just while patients are being treated, but up to 1 year later.

Hubert Lim, a biomedical engineer at the University of Minnesota, Twin Cities, hit on the role of the tongue in tinnitus by accident. A few years ago, he experimented with using a technique called deep brain stimulation to restore his patients’ hearing. When he inserted a pencil-sized rod covered in electrodes directly into the brains of five patients, some of those electrodes landed slightly outside the target zone—a common problem with deep brain stimulation, Lim says. Later, when he started up the device to map out its effects on the brain, a patient who had been bothered by ringing ears for many years, said, “Oh, my tinnitus! I can’t hear my tinnitus,” Lim recalls.

With certain kinds of tinnitus, people hear real sounds. For instance, there might be repeated muscular contractions in the ear, Lim says. But for many people, it’s the brain that’s to blame, perceiving sounds that aren’t there. One potential explanation for the effect is that hearing loss causes the brain to overcompensate for the frequencies it can no longer hear.

Further testing in guinea pigs revealed the best body parts to stimulate to shut off tinnitus, Lim says. He and colleagues tested the ears, neck, limbs, and “you know … other places,” he says, eventually concluding the tongue was the best target.

Then Lim turned to humans. In the team’s experiment, 326 people with tinnitus sat for up to 1 hour at a time with a small plastic paddle on their tongue. Tiny electrodes in the paddle delivered an electrical current designed to broadly excite the brain, getting activity going through a number of interconnected regions. The electrical stimulation feels a little like pop rocks candy fizzing in your mouth, Lim says.

Subjects also wore headphones that delivered a more targeted hit to the brain’s auditory system. Each person heard a rapidly changing series of pure tones at different frequencies, against a background noise that sounds “kind of like electronic music,” Lim says. The goal of the two together was to distract the brain by heightening its sensitivity, forcing it to suppress the activity that causes tinnitus. “The brain can only pay attention to so many things,” Lim says.

Over the 12 weeks of treatment, the patients’ tinnitus symptoms improved dramatically. More than 80% of those who complied with the prescribed regimen saw an improvement. And they saw an average drop of about 14 points on a tinnitus severity score of one to 100, the researchers report today in Science Translational Medicine. When the team followed up after 12 months, 80% of the participants still had lower tinnitus scores, with average drops of 12.7 and 14.5 points.

The results are “quite impressive,” Cederroth says. The reduction in symptoms is larger than other studies have found for bimodal stimulation, he says, and it’s the first evidence of such long-term effects. A 2018 paper that stimulated the skin on the neck and cheek over a shorter time improved patients’ tinnitus, but there was a smaller dip in severity scores, he notes, of only about seven points. And cognitive behavioural therapy, a kind of talk therapy that is currently the only clinically validated tinnitus therapy, improves severity scores by about 10 points on average.

Still, University of Oxford neuroscientist Victoria Bajo notes there was no control group in the trial. Without that, she says, it’s impossible to know how much patients would have improved on their own or with a placebo. The work is good, she says, “but this is the beginning."

[ Source:]

Read more about Ayurvedic Management of Tinnitus .

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Monday, October 12, 2020

What is Pink Moon milk?

 Tossing and turning throughout the night can be the most agonizing experience. Sleepless nights can leave you feeling drained.

There’s no denying the fact that there are several over the counter pills and supplements that claim to fix lack of sleep and disturbed sleep patterns, but in the long run, these sedatives can take a toll on your overall health and mental wellbeing.

If you too have been struggling to get that soul-relieving sleep, then falling back to the basics may be the best resort. Pink Moon milk is that perfect Ayurvedic blend that you can include in your diet to get that perfect good night sleep. A fad among health enthusiasts, Pink Moon milk is basically Ashwagandha milk, this age-old sleep elixir is believed to be the best sleep inducer. 

Ashwagandha is packed with healing properties that help in relieving stress, anxiety, inflammation and helps in boosting brain health. Adding this miraculous herb to your milk or herbal tea can improve your overall health and boost up your immunity.

How to prepare Pink Moon milk?

- To make this sleep elixir, take a pan over medium flame and add in 1 cup milk, allow the milk to heat at low flame.

- Then add in ½ teaspoon Ashwagandha powder, ½ teaspoon cinnamon powder, a pinch of nutmeg, 2 crushed almonds, 1/2 teaspoon coconut oil, 1 teaspoon honey. Whisk it well.

- Lastly, add in a dash of turmeric and 1 tablespoon dried crushed rose petals. Allow the blend to boil and drink it warm.

Read more about Medicinal Properties of Ayurvedic Herb - Ashwagandha

Read about more Ayurvedic remedies for Sleeplessness